I have some experience here, as before I went ampless I had a 2X10 Hard Trucker cabinet with a pair of K-110s I had custom made by HT and a standard HT 2X12 with a pair of E-120s.
Subjectively, in a room with just the guitar, back to back, the K-110 is a sweeter sounding speaker. It just sounds nice and warm. Really nice. The E-120, in comparison, is much harsher and strident to the ears, very sterile, little warmth.
In the mix, the E-120 cuts through like a knife and it's "that" sound. The K-110 does not cut through as well and it sounds thinner, which is not what you might expect.
(This is exactly what I used to find live when I would use a Twin head with E-120s and swap for a Vibrolux with a pair K-110s at smaller gigs. Sounded nicer alone, didn't cut through the mix.)
In fact, I made impulse response files of both cabinets to use with my Fractal equipment and found exactly the same listening back to multitracks, the K-110 just does not have the same bite and will not cut through the mix as well as the E-120. I use the E-120 IR file live.
So, if you're playing live with a band, the extra weight of the E-120s is well worth it. If you're playing for fun in your living room, you will enjoy the K-110s.